Endocrine Abstracts

Introduction: Intrathyroidal parathyroid adenomas (IPA) are a rare cause of primary hyperparathyroidism (PHP) and their differential diagnosis includes other parathyroid and thyroid lesions. Although <7% of parathyroid adenomas are intrathyroidal, this location represents almost 20% of ectopic cases and their preoperative identification can pose difficulties, often being an intraoperative finding.Clinical case: A 70-year-old woman diagnosed with brea...

Introduction: Depression, anxiety and eating disorders appear more frequently in patients with type 2 diabetes and are associated with worse metabolic control and higher risk of developing micro and macrovascular complications. The aim of this study was to determine the prevalence of psychiatric comorbidities in diabetic patients, candidates for therapy with SGLT2 inhibitors (SGLT2i) and to evaluate their clinical profile and degree of metabolic control before beginning the tr...

Introduction: Asymptomatic, mild or moderate elevations of creatine phosphokinase are frequently found in hypothyroidism, but rhabdomyolysis is rare, and even more so when it constitutes its clinical presentation.Clinical case: A 26-year-old male who regularly practiced sports, with no family or personal history of interest, went to the emergency room referring to myalgia, generalized cramps, and muscular weakness in the previous two weeks which had not ...

Context: Primary hyperparathyroidism (PHPT) is a common endocrine disease, characterized by the chronic elevation of serum calcium (Ca) levels induced by a long-standing increase of PTH concentrations. PHPT includes mild-asymptomatic and symptomatic forms. Cinacalcet is effective in lowering serum Ca levels in PHPT, but is indicated solely in mild-asymptomatic PHPT meeting surgery criteria. Management of non-surgical mild-asymptomatic PHPT is still a debated issue.<p class...

Objectives: To study vitamin D deficiency in a cohort of obese males and to evaluate associated clinical and biochemical characteristics.Methods: Case-control study which included obese (defined by a BMI ≥30 kg/m2) males. Vitamin D deficiency was defined as vitamin D levels <20 ng/ml. Estimation of vitamin D status was determined in serum using a commercially available enzyme- immuno-assay designed to measure 25-OH Vitamin D concentr...